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(A–C) NPTRM test (A) valid erections; (B) time of circumference increase, (C) maximum rigidity) in patients with normal m-IMT, increased m-IMT and with atherosclerotic plaques in basal conditions and after 30 days from tadalafil non-on demand treatment cessation. Only patients with atherosclerotic plaques do not improve after treatment, whereas the other 3 groups (young controls, IMT < 0.9 mm, IMT 0.9–1.2 mm) show significant (&) improvement. The inter-group variations show that in basal conditions there is a negative trend between IMT and NPTRM parameters, whilst after treatment IMT 0.9–1.2 mm group has overlapping results respect to IMT < 0.9 mm.
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