Two potential targets for preventing chronic lower urinary tract symptoms (LUTS) in older men are obesity and physical activity.
To examine associations of adiposity and physical activity with incident LUTS in community-dwelling older men.
Design, setting, and participants
The Osteoporotic Fractures in Men Study (MrOS) is a prospective cohort of men ≥65 yr of age. MrOS participants without LUTS and a history of LUTS treatment at baseline were included in this analysis.
Adiposity was measured with body mass index (BMI), physical activity with the Physical Activity Scale for the Elderly (PASE) and self-report of daily walking, and LUTS with the American Urological Association Symptom Index.
Results and limitations
The mean age (standard deviation [SD]) of the 1695 participants was 72 (5) yr at baseline. At a mean (SD) follow-up of 4.6 (0.5) yr, 524 (31%) of men reported incident LUTS. In multivariate analyses, compared with men of normal weight at baseline (BMI <25
In older men, obesity and higher physical activity are associated with increased and decreased risks of incident LUTS, respectively. Prevention of chronic urinary symptoms represents another potential health benefit of exercise in elderly men.
Keywords: LUTS, Epidemiology, BPH, Benign prostatic hyperplasia, Obesity, Exercise, Physical activity, Prostate, IPSS.
a Division of Urology, University of California San Diego, San Diego, CA, USA
b Urologic Cancer Unit, Moores UCSD Cancer Center, La Jolla, CA, USA
c Department of Surgery, San Diego Veterans Affairs Medical Center, La Jolla, CA, USA
d Division of Biostatistics, Moores UCSD Cancer Center, La Jolla, CA, USA
e Department of Family and Preventive Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA
f Department of Medicine, University of California San Francisco, San Francisco, CA, USA
g Department of Medicine, Bone and Mineral Unit, Oregon Health and Science University, Portland, OR, USA
h Department of Orthopaedics and Rehabilitation, Oregon Health and Science University, Portland, OR, USA
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© 2011 European Association of Urology, Published by Elsevier B.V.