Journal Article Page
European UrologyVolume 58, issue 6, pages e53-e62, December 2010
Careful Selection and Close Monitoring of Low-Risk Prostate Cancer Patients on Active Surveillance Minimizes the Need for Treatment
Accepted 12 August 2010, Published online 20 August 2010, pages 831 - 835
Our data suggest that if the guidelines for AS are narrowly defined to include only those patients with Gleason score 6, PSA levels ≤10, and tumor volume ≤20% in two or fewer cores, a lower percentage of AS patients will likely require treatment when compared to other AS series. In our experience, the PFS appears to be equivalent to those who initiated treatment at diagnosis. With careful selection and close monitoring of LRPC, the dilemma regarding overtreatment and its impact on HRQoL, which may already be impaired at diagnosis, may be less of a dilemma—if and when AS is accepted as a viable alternative.
© 2010 European Association of Urology, Published by Elsevier B.V.
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