This review focuses on the prevention and management of complications following radical cystectomy (RC) for bladder cancer (BCa).
We review the current literature and perform an analysis of the frequency, treatment, and prevention of complications related to RC for BCa.
A Medline search was conducted to identify original articles, reviews, and editorials addressing the relationship between RC and short- and long-term complications. Series examined were published within the past decade. Large series reported on multiple occasions (Lee , Meyer , and Chang and Cookson ) with the same cohorts are recorded only once. Quality of life (QoL) and sexual function were excluded.
The literature regarding prophylaxis, prevention, and treatment of complications of RC in general is retrospective, not standardised. In general, it is of poor quality when it comes to evidence and is thus difficult to synthesise.
Progress has been made in reducing mortality and preventing complications of RC. Postoperative morbidity remains high, partly because of the complexity of the procedures. The issues of surgical volume and standardised prospective reporting of RC morbidity to create evidence-based guidelines are essential for further reducing morbidity and improving patients’ QoL.
Keywords: Bladder carcinoma, Cystectomy, Adverse effects, Urology, Surgery, Review.
a Division of Urology, Department of Surgical Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Canada
b Department of Urology, University “Vita-Salute” - San Raffaele Hospital, Milan, Italy
c Department of Urology, Rostock University, Rostock, Germany
d Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA
e Department of Urology, Skåne University Hospital, Lund, Sweden
f Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
g Department of Urology, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany
Corresponding author. University of Toronto, Surgical Oncology, 610 University Ave, Ste 3-130, Princess Margaret Hospital, Toronto, M5G2M9 Canada.
© 2010 Published by Elsevier B.V.