Case Study of the Month

Neoadjuvant Sutent Induction Therapy May Effectively Down-Stage Renal Cell Carcinoma Atrial Thrombi eulogo1

By: Pierre I. Karakiewicza lowast , Nazareno Suardia, Claudio Jeldresa, Pascale Audeta, Pierre Ghosna, Jean-Jacques Patardb and Paul Perrottea

European Urology, Volume 53 Issue 4, April 2008, Pages 845-848

Published online: 01 April 2008

Keywords: Renal cancer, Sunitinib, Thrombus

Abstract Full Text Full Text PDF (533 KB)


A 75-yr-old previously healthy woman presented with gross hematuria, European Cooperative Oncology Group 0, and an 11-cm renal mass with right atrial thrombus. The patient refused the sternotomy. She was offered two cycles of sunitinib maleate (Sutent) induction therapy to down-stage the thrombus and to reduce the extent of the surgery.

Keywords: Renal cancer, Sunitinib, Thrombus.


a Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, QC, Canada

b Department of Urology, Rennes University Hospital, Rennes, France

Corresponding author. Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center (CHUM), 1058, rue St-Denis, Montréal, QC H2X 3J4, Canada. Tel. +1 514 890 8000 35336; Fax: +1 514 227 5103.

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