European Urology

European Urology

Volume 49, issue 3, pages 415-594, March 2006

Reviews

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2005 Update on Pathology of Prostate Biopsies with Cancer

Rodolfo Montironi, Remigio Vela-Navarrete, Antonio Lopez-Beltran, Roberta Mazzucchelli, Aldo Bono.

Accepted 29 November 2005, Published online 4 January 2006, pages 441 - 447


Abstract

Objective

To review the diagnostic and prognostic importance of pathologic findings in prostate biopsies.

Materials and Results

While the primary goal of the biopsy is to diagnose prostatic adenocarcinoma, once carcinoma is detected, information regarding the type, amount, and grade of cancer forms the cornerstone for contemporary management of the patient and for assessment of the potential for local cure and the risk for distant metastasis.

Conclusions

The novelty of this 2005 update is represented by a detailed morphologic and immunohistochemical description of prostatic adenocarcinoma features in biopsies.

Keywords: Prostate cancer, Biopsy, Diagnosis, Prognosis.


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