European Urology

European Urology

Volume 49, issue 1, pages 1-208, January 2006

[Editorial Comment by Karl-Dietrich Sievert]

Reinnervation for Neurogenic Bladder: Historic Review and Introduction of a Somatic-Autonomic Reflex Pathway Procedure for Patients with Spinal Cord Injury or Spina Bifida

Chuan-Guo Xiao.

Accepted 10 October 2005, Published online 2 November 2005, pages 22 - 29


Abstract

Neurogenic bladder caused by SCI or spina bifida is a major problem. Research in restoring functional micturition has mainly focused on electrical stimulation for many decades with good progress, but it is still not the definitive solution for majority of the SCI patients.

An alternative approach has been to investigate restoring innervation to the lower urinary tract after spinal SCI. Different animal and clinical studies were reviewed historically in this article, focused on mainly cross over nerve surgery for reinnervation of the bladder. An artificial somatic-autonomic reflex pathway procedure and its mechanisms were introduced. Clinical application and the satisfactory results of the new procedure were reviewed in details in restoring voluntary bladder control in patients with SCI or spina bifida.

Keywords: Neurogenic, Spinal cord injury, Spina bifida, Bladder reinnervation, Neurosurgical procedure.


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