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European Urology
Volume 48, issue 1, pages 1-178, July 2005Prostate Cancer
Dietary Intake of Calcium, Vitamin D, Phosphorus and the Risk of Prostate Cancer
Accepted 22 March 2005, Published online 8 April 2005, pages 27 - 33
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Abstract
Objectives:
A relation of prostate cancer risk with calcium, vitamin D and phosphorus has been suggested, but remains controversial.
Methods:
A case-control study was conducted in Italy in 1991–2002. Cases were 1294 men with incident prostate cancer, and controls were 1451 men admitted to hospital for acute non-neoplastic diseases. Odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated using unconditional multiple logistic regression.
Results:
Compared to the lowest one quintile of dietary calcium intake the OR was 1.18 for the highest, 1.01 for an increment of 622 mg/day of calcium, and 1.29 (95% CI 0.78–2.13) for 2000 mg/day or more of calcium. The OR of prostate cancer for the highest quintile of dietary intake of vitamin D and phosphorus were 1.33 and 1.20 respectively.
Conclusions:
This study shows no material association of dietary intake of calcium, vitamin D and phosphorus with prostate cancer risk.
Keywords: Calcium, Case-control study, Phosphorus, Prostate cancer, Risk factors, Vitamin D.
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